Figure 1: Mild erythema observed on left lower limb

Figure 2: Mild edema observed on left lower limb as compared to the right side

Figure 3: Color-Doppler ultrasound of left deep femoral vein before compression, showing hyper echogenic thrombus

Figure 4: Color-Doppler ultrasound of left deep femoral vein after compression, showing non-compressible thrombotic lesion

Figure 5: Coagulation cascade. Solid arrows represent activation events, dashed arrows represent inhibition events, and dotted lines with circles represent inactivation events. a = active; APC = activated protein C; F = factor; FDP= fibrin degradation products; HMW = high molecular weight; PAI-1 = plasminogen activator inhibitor-1; PL = phospholipid; TM = Thrombomodulin; t-PA = tissue type plasminogen activator; u-PA = Urokinase plasminogen activator; XL= Cross-linked (Scott C Howard, Hassan M Yaish, et al, pediatric thromboembolism, Aug 23, 2016.)

Inherited Disorders
Factor V Leiden mutation
Prothrombin gene mutation
Protein S deficiency
Protein C deficiency
Antithrombin deficiency
Other rare disorders

Table 1: Inherited Disorders Causing DVT [2]

Acquired Disorders
Arterial or central venous catheters
Congestive heart failure
Antiphospholipid antibody syndrome
Surgery, especially orthopedic
Myeloproliferative disorders
Heparin induced thrombocytopenia
PNH, sickle cell disease
DIC, sepsis, hypovolemia
Hormone replacement therapy, OCPs Tamoxifen, Thalidomide, Lenalidomide
Essential thrombocythemia, polycythemia vera
Nephrotic syndrome
Anatomical compression

Table 2: Acquired Disorders Causing DVT [12]